Prof Solomon P. Wasser – Lingzhi (Reishi) and Cancer

Prof. Solomon P. Wasser, D.Sc serves as a Member of Scientific Advisory Board at Mycobiotech Ltd and Institute of Evolution, University of Haifa, Mount Carmel, Haifa, Israel. Solomon P. Wasser is the world renowned expert on Reishi (Ling Zhi), author and co-author of over 400 scientific publications including 34 books and 12 patents in the USA and former USSR for new strains of edible and valuable medicinal mushrooms.

Excellent research paper by Prof. Solomon P. Wasser. Here are some information I extracted from one of his paper. I can’t seem to find when he wrote this paper though.


The mechanisms for the tumor preventive and antitumor effect of G. lucidum. Active constituents from G. lucidum may operate through several mechanisms including enhancement of detoxification of carcinogens (line 1), increased expression and activity of Phase II enzymes (line 2), inhibition of organ exposure of carcinogens due to reduced absorption or increased excretion (line 3), decreased expression and activity of Phase I (e.g., CYPs) enzymes (line 4), decreased formation of toxic metabolites and adduct formation with macromolecules (line 5), enhanced host immune responses (e.g., activation of macrophages, T lymphocytes, and natural killers producing various cytokines such as TNF-a, IFNs, and ILs, which improve immunosurveillance and kill preneoplastic and cancer cells) (line 6), antioxidative and radical-scavenging effects (line 7), antipromotion effect (line 8), antiproliferation (line 9), apoptosis induction of tumor cells (line 10), induction of differentiation (line 11), direct cytotoxicity, induction of cell-cycle arrest, antiproliferation and modulation of signaling transduction molecules (line 12), antiprogression and tumor growth inhibition (line 13), antimetastasis (line 14), and anti-angiogenesis (line 15).

Applications Observed effects
Usage with conventional treatment in cancer therapy 1. Maintains leukocyte counts
2. Enhances the immune system
3. Reduces chemotherapy toxicity and elimination of induced leucopenia (low blood leukocytes) by chemotherapy and radiation
4. Accelerates postsurgical recovery
5. Sedation, pain relief and reduction of morphine dependence in terminal cancer patients
6. Usage during remission to prevent relapses
Immunomodulation effects 1. Anticancer
2. Antiviral (e.g., anti-HIV)
3. Antibacterial
4. Anti-inflammatory
5. Therapy of autoimmune disorders
6. Inhibition of histamine release in allergy and prevention of aphylactic shock

Related Link – Research Article – Lingzhi (Ganoderma) & Cancer Treatment